国际眼科纵览 ›› 2023, Vol. 47 ›› Issue (1): 18-24.doi: 10.3760/ cma.j.issn.1673-5803.2023.01.004

• 综述 • 上一篇    下一篇

原发性急性房角关闭的危险因素

司姣1 陶宇菲1 樊宁2   

  1. 1 暨南大学第二临床医学院,深圳 518040;2 深圳市眼科医院 暨南大学附属深圳眼科医院,深圳 518040
  • 收稿日期:2022-10-13 出版日期:2023-02-22 发布日期:2023-03-10
  • 通讯作者: 樊宁,Email:szfanning@126.com E-mail:szfanning@126.com
  • 基金资助:
    国家自然科学基金(82271087);广东省基础与应用基础研究基金项目(2019A1515011234);深圳市科创委基础研究项目(JCYJ20190807153005579)

Risk factors for acute primary angle closure

Si Jiao1, Tao Yufei1, Fan Ning2   

  1. 1 The Second Clinical Medical College, Jinan University, Shenzhen 518040, China; 2 Shenzhen Eye Hospital, Jinan University, Shenzhen 518040, China
  • Received:2022-10-13 Online:2023-02-22 Published:2023-03-10
  • Contact: Fan Ning, Email: szfanning@126.com E-mail:szfanning@126.com
  • Supported by:
    National Natural Science Foundation of China (82271087); Guangdong Basic and Applied Basic Research Foundation (2019A1515011234); Science and Technology Innovation Committee of Shenzhen (JCYJ20190807153005579)

摘要: 原发性急性房角关闭(acute primary angle closure, APAC)是一种常见的眼科急症,致盲率高。诱发APAC的病理机制尚未完全阐明,与APAC发病相关的解剖参数包括拥挤狭窄的前房和房角结构、增厚前移且不稳定的晶状体、较薄的睫状体与肥厚前移的睫状突、动态变化的虹膜和脉络膜等。在一些诱发因素(情绪、极端天气和药物等)下,这类危险人群的单眼或双眼的单个或多个解剖参数发生改变,导致APAC发病。(国际眼科纵览,2023, 47:18-24)

关键词: 原发性急性房角关闭, 危险因素

Abstract: Acute primary angle closure (APAC) is an ocular emergency and requires immediate management to avoid blindness. The pathological mechanisms inducing APAC have not been entirely understood. Recent studies summarized the anatomical parameters associated with APAC, including crowded anterior chamber and angle, thicken and anterior moving lens, thinner ciliary body and expansive anterior rotating ciliary process, dynamic changing iris and choroid. Changes in single or multiple anatomical parameters of one or both eyes in such risk groups lead to the onset of APAC, under some predisposing factors (emotions, extreme weather and drugs, etc). (Int Rev Ophthalmol, 2023, 47: 18-24)

Key words: acute primary angle closure, risk factor